Aromatic di-keto derivatives as glucose-6-phosphate...

C - Chemistry – Metallurgy – 07 – C

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Details

C07C 65/40 (2006.01) A61K 31/19 (2006.01) A61K 31/34 (2006.01) A61P 3/10 (2006.01) C07D 307/20 (2006.01) C07D 493/20 (2006.01)

Patent

CA 2388957

The present invention relates to new aromatic di-keto derivatives and to their pharmaceutically acceptable salts, esters, ethers and other obvious chemical equivalents. The derivatives are glucose-6-phosphate translocase inhibitors and can be used in the treatment of diabetes mellitus. The present invention further relates to a process for the production of the derivatives, to the use of the derivatives and their pharmaceutically acceptable salts, esters, ethers and other obvious chemical equivalents as pharmaceuticals, in particular to their use in the treatment of diabetes mellitus, and to pharmaceutical compositions comprising the derivatives, pharmaceutically acceptable salts, esters, ethers or other obvious chemical equivalents thereof.

La présente invention concerne de nouveaux dérivés di-céto aromatiques ainsi que leurs sels, esters, éthers et autres équivalents chimiques évidents acceptables sur le plan pharmaceutique. Les dérivés sont des inhibiteurs de glucose-6-phosphate translocase et ils peuvent être utilisés dans le traitement du diabète sucré. L'invention concerne également un procédé de production des dérivés, l'utilisation des dérivés et de leurs sels, esters, éthers et autres équivalents chimiques évidents, acceptables sur le plan pharmaceutiques, en tant qu'agents pharmaceutique, en particulier leur utilisation dans le traitement du diabète sucré, ainsi que des compositions pharmaceutiques contenant les dérivés, des sels, des esters, des éthers ou autres équivalents chimiques évidents de ceux-ci, acceptables sur le plan pharmaceutique.

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