Aromatic heterocyclic compounds as anti-inflammatory agents

Details Aromatic heterocyclic compounds as anti-inflammatory agents Aromatic heterocyclic compounds as anti-inflammatory agents

C - Chemistry, Metallurgy

07

D

C07D 333/36 (2006.01) A61K 31/38 (2006.01) A61K 31/415 (2006.01) C07D 231/40 (2006.01) C07D 235/30 (2006.01)

Patent

CA 2308428

Novel aromatic heterocyclic compounds inhibit cytokines production involved in immunoregulation and inflammation such as interleukin-1 and tumor necrosis factor production. The compounds are therefore useful in pharmaceutic compositions for treating diseases or pathological conditions involving inflammation such as chronic inflammatory diseases.

Les composés hétérocycliques aromatiques de l'invention bloquent la production de cytokines impliquées dans l'immunorégulation et l'inflammation et notamment la production de l'interleukine IL-1 et le facteur de nécrose tumorale. Ces composés conviennent donc pour des compositions pharmaceutiques destinées au traitement d'affections ou d'états pathologiques impliquant des phénomènes inflammatoires, et notamment les maladies inflammatoires chroniques.

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