Aromatic steroid 5-–-reductase inhibitors

Details Aromatic steroid 5-–-reductase inhibitors Aromatic steroid 5-–-reductase inhibitors

C - Chemistry, Metallurgy

07

J

167/191, 260/57,

C07J 41/00 (2006.01) A61K 31/56 (2006.01) C07J 1/00 (2006.01) C07J 3/00 (2006.01) C07J 7/00 (2006.01) C07J 9/00 (2006.01) C07J 13/00 (2006.01) C07J 21/00 (2006.01) C07J 31/00 (2006.01) C07J 43/00 (2006.01)

Patent

CA 1331457

ABSTRACT OF THE DISCLOSURE AROMATIC STEROID 5-.alpha.-REDUCTASE INHIBITORS Invented are substituted acrylate analogues of steroidal synthetic compounds, pharmaceutical compositions containing the compounds, and methods of using these compounds to inhibit steroid 5-.alpha.-reductase including using these compounds to reduce prostate size. Also invented are intermediates used in preparing these compounds.

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