Arphemenine-related compounds and uses thereof

C - Chemistry – Metallurgy – 07 – D

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C07D 239/42 (2006.01) A61K 31/505 (2006.01)

Patent

CA 1253499

NEW ARPHAMENINE-RELATED COMPOUNDS AND USES THEREOF ABSTRACT OF THE DISCLOSURE New arphamenine-related compounds are now provided, which are represented by the formula (I) Image wherein R1 denotes a hydrogen atom or an amino-protecting group, R2 denotes a dimethylpyrimidinyl group, R3 denotes a hydrogen atom or a hydroxyl group, and R4 denotes a hydrogen atom or a carboxyl-protecting group. The new arphamenine-related compounds exhibit a carboxypeptidase- inhibitory activity and also an immunopotentiating activity and are useful for potentiating the immune response in a living animal.

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