Arrays, methods and kits for preparation and use of syntenic...

C - Chemistry – Metallurgy – 40 – B

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C40B 40/06 (2006.01) C12Q 1/68 (2006.01) C40B 30/06 (2006.01)

Patent

CA 2534441

The invention provides arrays, array-based methods, apparatuses and kits for detecting genetic abnormalities in cell populations, such as biopsy or body fluid samples or cultures of cancer cells, for comparing syntenic chromosome strans of different species, thereby optimizing performance of an array-based genomic hybridization.

L'invention concerne des jeux ordonnés d'échantillons, des procédés fondés sur des jeux ordonnés d'échantillons, des appareils et des kits de détection d'anomalies génétiques dans des populations cellulaires, de type biopsie ou échantillons de liquides biologiques ou cultures de cellules cancéreuses, destinés à comparer des souches de chromosomes synténiques d'espèces différentes, ce qui permet d'optimiser la performance d'une hybridation génomique fondée sur des jeux ordonnés d'échantillons.

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