Arteriosclerosis remedy

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/12 (2006.01) A61K 31/70 (2006.01) A61K 48/00 (2006.01) C07K 14/47 (2006.01) C12N 15/85 (2006.01)

Patent

CA 2172978

Therapeutic agents for arteriosclerosis, which comprise a calponin gene as an active ingredient are provided. The therapeutic agents for arteriosclerosis of the present invention are useful for suppressing the intimal hyperplasia of blood vessels. Hence, the therapeutic agents for arteriosclerosis of the present invention are effective against arteriosclerosis and ischemic heart diseases it induces, such as angina pectoris and cardiac infarction and, in particular, they are very effective in preventing restenosis after PTCA.

L'invention concerne un médicament contre l'artériosclérose contenant un gène de carponine en tant que principe actif et capable d'inhiber l'épaississement de l'endartère. Ce médicament est par conséquent efficace pour le traitement de l'artériosclérose et des cardiopathies ischémiques en découlant telles que l'angine de poitrine et l'infarctus du myocarde. Plus particulièrement, il s'avère remarquablement efficace pour inhiber l'apparition de la resténose après une angioplastie coronarienne transluminale percutanée.

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