Article to be inserted in a body cavity having biologically...

A - Human Necessities – 61 – L

Patent

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A61L 29/14 (2006.01)

Patent

CA 2646639

An article to be inserted in a human or animal body cavity, use of the article and preparation thereof. The article has a biologically inhibiting arrangement of electrically connected electrode materials in direct contact with each other on one or more surfaces of the article The arrangement includes as electrode materials a metallic anode material and a cathode material, where the potential of the cathode material is higher than the potential of the anode material, The cathode material is an electrically conductive material selected among certain non-metallic materials. The arrangement provided on the article releases biological inhibiting ions of the metallic anode material or complexes of such ions when the biologically inhibiting arrangement is contacted with a body fluid. The article can be designed with a controlled release rate suitable for the purpose in question for example an initial high rate of ion release after insertion of a catheter to combat bacteria introduced during the insertion followed by a prolonged release at a lower rate to maintain a low level of bacteria.

Article conçu pour être inséré dans une cavité corporelle humaine ou animale, utilisation de cet article et sa préparation. Cet article possède un système d'inhibition biologique de matériau d'électrodes couplées en contact direct l'une avec l'autre sur une ou plusieurs surfaces de l'article. Ce système comprend en tant que matériau d'électrode, un matériau anodique métallique et un matériau cathodique, le potentiel du matériau cathodique étant supérieur à celui du matériau anodique. Le matériau cathodique consiste en un matériau conducteur sélectionné dans certains matériaux non métalliques. Le système que comporte cet article libère des ions d'inhibition biologique du matériau anodique métallique ou des complexes de ces ions quand ce système est mis en contact avec un fluide corporel. Cet article peut intégrer un mode de libération contrôlée permettant, par exemple, de libérer un taux initial élevée d'ions après l'insertion d'un cathéter servant à lutter contre les bactéries introduites pendant l'insertion suivie par une libération prolongée à un taux inférieur, de manière à maintenir un niveau bas de bactéries.

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