Articles of manufacture and methods for staining biomolecules

G - Physics – 01 – N

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G01N 1/30 (2006.01) C12Q 1/68 (2006.01) G01N 33/543 (2006.01)

Patent

CA 2321100

Biomolecules contained in gels or on membranes can be stained or labeled, without direct contact with toxic staining solutions, by applying to the gel or membrane an article of manufacture comprising a flexible backing with a coating that contains a stain or label. During the application, the stain or label is transferred from the backing to the biomolecules, marking them. The volume of the staining solution in this procedure is minimized, and environmental hazards are reduced. Furthermore, ease of manufacture reduces the cost of the article.

Il est possible de marquer ou de colorer des biomolécules qui sont contenues dans des gels ou qui sont situées sur des membranes sans qu'il existe de contact direct avec les solutions toxiques de coloration, pour ce faire, on applique sur le gel ou sur la membrane un article manufacturé comprenant un support souple doté d'un revêtement contenant une coloration ou une marque. Pendant l'application, la coloration ou la marque est transférée du support sur les biomolécules, ceci ayant pour effet de marquer ces dernières. Le volume de solution de coloration utilisé dans cette technique est réduit au maximum, et les dangers pour l'environnement sont per conséquent réduits. De plus, la facilité de la fabrication réduit le coût de l'article.

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