A - Human Necessities – 61 – L
Patent
A - Human Necessities
61
L
A61L 27/00 (2006.01)
Patent
CA 2732907
Disclosed is an artificial bone material having controlled calcium ion elution, which does not induce cytotoxicity or any inflammatory response. It is found that the elution of a calcium ion from an artificial bone material for transplantation which contains a calcium-containing substance can be prevented effectively by subjecting the carrier to a surface treatment or adding a surface-treating agent to the carrier. It is also found that the induction of cytotoxicity can be prevented and the induction of an inflammatory response can also be prevented by using the above-mentioned carrier having controlled calcium ion elution.
La présente invention concerne un matériau dos artificiel avec une élution dion calcium contrôlée, qui ninduit pas la cytotoxicité ni aucune réponse inflammatoire. On a découvert quil est possible déviter efficacement lélution dun ion calcium à partir dun matériau dos artificiel pour greffe qui comporte une substance contenant du calcium, en soumettant le vecteur à un traitement de surface ou en ajoutant un agent de traitement de surface au vecteur. On a également découvert quil est possible déviter linduction de la cytotoxicité et dempêcher linduction dune réponse inflammatoire en utilisant le vecteur susmentionné avec une élution dion calcium contrôlée.
Sasaki Nobuo
Suzuki Shigeki
Tei Yuichi
Borden Ladner Gervais Llp
Next21 K.k.
The University Of Tokyo
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