Artificial extracellular matrix and process for producing...

Details Artificial extracellular matrix and process for producing... Artificial extracellular matrix and process for producing...

A - Human Necessities

61

L

A61L 27/24 (2006.01) A61K 38/39 (2006.01) A61L 27/38 (2006.01) A61L 27/44 (2006.01) A61L 27/56 (2006.01) A61L 27/58 (2006.01) A61L 27/60 (2006.01)

Patent

CA 2485914

An artificial extracellular matrix containing heat-stabilized fish-origin collagen wherein the heat stability of the fish-origin collagen, which inherently has a heat-denaturation temperature of lower than 37 ~ C, has been improved. Because of having an appropriate stabilityin vivo and a function of highly activating tissue repair, the artificial extracellular matrix has no need for further blending with heat-denatured collagen. Moreover, it contains the fish-origin collagen and thus has little risk of being contaminated with pathogens.

L'invention concerne une matrice extracellulaire artificielle contenant du collagène issu des poissons à stabilisation thermique, la stabilité thermique du collagène issu des poissons, qui, par nature, présente une température de dénaturation thermique inférieure à 37 ·C, a été améliorée. En raison d'une stabilité convenable in vivo et d'une fonction d'activation élevée de réparation des tissus, la matrice extracellulaire ne doit pas être davantage mélangée avec du collagène à dénaturation thermique. De plus, la matrice contient le collagène issu des poissons et par conséquent ne risque pas d'être contaminée par des pathogènes.

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