Artificial mutation controls for diagnostic testing

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 5/10 (2006.01) C07H 21/00 (2006.01) C12N 1/21 (2006.01) C12N 15/09 (2006.01) C12N 15/10 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2558641

Disclosed are artificial compositions that can be used as positive controls in a genetic testing assay, such as a diagnostic assay for a particular genetic disease. Such controls can be used to confirm the presence or absence of a particular mutation. Also provided are methods of generating such compositions, and methods of their use.

L'invention concerne des compositions artificielles pouvant être utilisées comme régulations positives dans un dosage de test génétique, tel qu'un dosage diagnostic destiné à dépister une maladie génétique particulière. Ces régulations peuvent être utilisées pour confirmer la présence ou l'absence d'une mutation particulière. L'invention concerne en outre des méthodes de production et d'utilisation desdites compositions.

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