Artificial neural tube

A - Human Necessities – 61 – F

Patent

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Details

A61F 2/04 (2006.01) A61L 27/00 (2006.01) A61L 27/18 (2006.01) A61L 27/22 (2006.01) A61L 27/24 (2006.01) A61L 27/58 (2006.01) A61F 2/02 (2006.01)

Patent

CA 2375595

An artificial neural tube which remains in the body until the completion of nerve regeneration but does not remain as a foreign matter thereafter, induces the regeneration of axon from a cut-end of a cut nerve, promotes the invasion of capillary blood vessels <i>in vivo</i>, and thus promotes the regeneration of a nerve tissue. Namely, an artificial neural tube composed of a tube made of a biodegradable material, a microfibrous collagen material inserted into the tube and laminin packed into the voids of the microfibrous collagen material; and a process for producing the artificial neural tube.

L'invention concerne un tube neural artificiel qui reste dans le corps jusqu'à ce qu'un nerf soit complètement régénéré mais ne se transforme pas en un corps étranger par la suite, ce tube neural provoquant la régénération d'un axone à partir de l'extrémité d'un nerf coupé, favorisant l'afflux de vaisseaux sanguins <i>in vivo</i>, et facilitant ainsi la régénération d'un tissu neural. Le tube neural artificiel selon l'invention consiste donc en un tube formé d'une matière biodégradable, d'une matière collagène microfibreuse introduite dans le tube et de laminine disposée dans les vides de la matière collagène microfibreuse. L'invention concerne aussi un procédé de production du tube neural artificiel.

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