Artificial peptidoglycan lysing enzymes and peptidoglycan...

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 14/435 (2006.01) C12N 9/14 (2006.01)

Patent

CA 2734829

The present invention relates to recombinant polypeptides having the activity of binding and lysing of bacteria, comprising at least one enzymatically active domain and at least two bacterial cell binding domains. The present invention further relates to recombinant polypeptide having the activity of binding bacteria, comprising at least two bacterial cell binding domain. Further the present inventions relates to nucleic acid molecules comprising a nucleotide sequence encoding the recombinant polypeptides, vectors and host cells.

La présente invention porte sur des polypeptides recombinés ayant l'activité de liaison à des bactéries et de lyse de celles-ci, comprenant au moins un domaine enzymatiquement actif et au moins deux domaines de liaison à des cellules bactériennes. La présente invention porte en outre sur un polypeptide recombiné ayant l'activité de liaison à des bactéries, comprenant au moins deux domaines de liaison à des cellules bactériennes. En outre la présente invention porte sur des molécules d'acide nucléique comprenant une séquence nucléotidique codant pour les polypeptides recombinés, sur des vecteurs et des cellules hôtes.

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