Artificial red cells and process for preparing same

Details Artificial red cells and process for preparing same Artificial red cells and process for preparing same

A - Human Necessities

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A61K 35/14 (2006.01) A61K 9/50 (2006.01) A61K 9/64 (2006.01) A61K 35/18 (2006.01) B01J 13/02 (2006.01) C07K 14/805 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1162850

ABSTRACT OF THE DISCLOSURE Artificial red cells comprising microdroplets of aqueous, stroma-free hemoglobin solution encapsulated in membranes of polymerized hemoglobin permeable to oxygen and impermeable to hemoglobin formed by a process compris- ing forming microdroplets of hemoglobin solution in a con- tinuous oil phase to form an emulsion of hemoglobin in oil and suspending globules of the so-formed emulsion in an aqueous suspending phase which contains a hemoglobin cross- linking agent which is at least bifunctional.

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