Artificial t helper cell epitopes as immune stimulators for...

A - Human Necessities – 61 – K

Patent

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Details

A61K 39/00 (2006.01) A61K 38/00 (2006.01) C07K 7/23 (2006.01) C07K 14/02 (2006.01) C07K 14/12 (2006.01)

Patent

CA 2330249

The present invention is directed to novel peptide immunogens for eliciting antibodies to LHRH comprising artificial T helper cell epitopes (Th epitopes) designed to provide optimum immunogenicity. The artificial Th epitopes are covalently linked to LHRH and optionally an immunostimulatory sequence.

L'invention concerne de nouveaux immunogènes de peptide permettant d'obtenir des anticorps contre LH-RH, comprenant des épitopes artificiels de lymphocytes T auxiliaires (épitopes Th) conçus pour fournir une immunogénicité optimum. Les épitopes artificiels T sont liés, de manière covalente, avec LH-RH, et éventuellement avec une séquence immunostimulatoire.

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