Artificial t helper cell epitopes as immune stimulators for...

Details Artificial t helper cell epitopes as immune stimulators for... Artificial t helper cell epitopes as immune stimulators for...

C - Chemistry, Metallurgy

07

K

C07K 14/00 (2006.01) A61K 39/385 (2006.01) A61P 37/02 (2006.01) C07K 7/08 (2006.01) C07K 7/23 (2006.01) C07K 14/09 (2006.01) C07K 14/16 (2006.01) C07K 14/445 (2006.01) C07K 14/47 (2006.01) C07K 14/655 (2006.01) C07K 14/73 (2006.01) C07K 16/00 (2006.01) C07K 19/00 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2329772

The present invention is directed to novel artificial T helper cell epitopes (Th epitopes) designed to provide optimum immunogenicity when used in peptide immunogens comprising B cell epitopes or peptide haptens, a target antigenic site of a target antigen for eliciting antibodies thereto. The artificial Th epitopes are covalently linked to the target antigenic site and and optionally an immunostimulatory sequence to provide effective and safe peptide immunogens.

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