C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/11 (2006.01) A01K 67/027 (2006.01) A61K 48/00 (2006.01) C12N 5/10 (2006.01) C12N 15/00 (2006.01) C12N 15/10 (2006.01) C12N 15/63 (2006.01) C12N 15/85 (2006.01) C12Q 1/68 (2006.01)
Patent
CA 2422533
The present invention relates to a polynucleotide comprising a ubiquitous chromatin opening element (UCOE) that does not occur in nature. The present invention also relates to a vector comprising the polynucleotide sequence, a host cell comprising the vector and use of the polynucleotide, vector or host cell in therapy, or for in vitro protein expression applications.
La présente invention concerne un polynucléotide comprenant un élément d'ouverture de la chromatine ubiquiste (UCOE) n'existant pas dans la nature. La présente invention concerne également un vecteur comprenant cette séquence polynucléotidique, une cellule hôte renfermant ce vecteur, ainsi que l'utilisation de ce polynucléotide, de ce vecteur ou de cette cellule hôte à des fins thérapeutiques ou dans des applications in vitro associées à l'expression protéique.
Antoniou Michael
Crombie Robert
Cameron Ip
Millipore Corporation
Ml Laboratories Plc
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