C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/18 (2006.01) A61K 35/14 (2006.01) A61L 27/38 (2006.01) A61L 27/50 (2006.01) C07K 14/52 (2006.01) C12N 5/06 (2006.01) C12N 5/08 (2006.01) C12N 15/12 (2006.01) C12N 15/63 (2006.01) A61F 2/06 (2006.01)
Patent
CA 2416548
The present invention provides an artificial vascular graft (10) and methods of generating same. The artificial vascular graft (10) includes a synthetic tubular element (12) having a luminal surface being coated with a plurality of endothelial cells and/or smooth muscle cells (16) being genetically transformed to express at least one cell proliferating growth factor and at least one cellular adherence factor.
L'invention concerne un greffon vasculaire artificiel et des procédés de fabrication correspondants. Le greffon vasculaire artificiel comprend un élément synthétique tubulaire possédant une surface luminale recouverte de plusieurs cellules endothéliales et/ou de muscle lisse, transformées génétiquement pour exprimer au moins un facteur de croissance de prolifération cellulaire et au moins un facteur d'adhérence cellulaire.
Cohen Tzafra
Flugelman Moshe Y.
Gluzman Zoya
Koren Belly
Preis Meir
M.g.v.s. Ltd.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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