Artificial vessels

C - Chemistry – Metallurgy – 12 – P

Patent

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Details

C12P 19/04 (2006.01) A61L 27/20 (2006.01) C08L 1/02 (2006.01)

Patent

CA 2665290

The present invention relates to an improved method for the preparation of hollow cellulose vessels produced by a microorganism, and hollow cellulose vessels prepared by this method. The method is characterized by the culturing of the cellulose-producing microorganisms being performed on the outer surface of a hollow carrier, and providing an oxygen containing gas on the inner side of the hollow carrier, the oxygen containing gas having an oxygen level higher than atmospheric oxygen. The hollow microbial cellulose vessels of the present invention are characterized by improved mechanical properties and can be used in surgical procedures to replace or repair an internal hollow organ such as the urethra, ureter, the trachea, a digestive tract, a lymphatic vessel or a blood vessel.

La présente invention concerne un procédé amélioré de préparation de vaisseaux creux en cellulose produits par un microorganisme et les vaisseaux creux en cellulose préparés avec ce procédé. Le procédé est caractérisé par la mise en culture des microorganismes producteurs de cellulose sur la surface extérieure d'un support creux et la fourniture d'un gaz contenant de l'oxygène sur le côté intérieur du support creux, le gaz contenant de l'oxygène ayant un niveau d'oxygène supérieur à celui de l'oxygène atmosphérique. Les vaisseaux microbiens de cellulose creux selon la présente invention sont caractérisés par des propriétés mécaniques améliorées et peuvent être utilisés dans des opérations chirurgicales visant à remplacer ou réparer un organe creux interne, par exemple l'urètre, l'uretère, la trachée, le conduit digestif, un vaisseau lymphatique ou un vaisseau sanguin.

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