Aryl amide sphingosine 1-phosphate analogs

Details Aryl amide sphingosine 1-phosphate analogs Aryl amide sphingosine 1-phosphate analogs

C - Chemistry, Metallurgy

07

F

C07F 9/40 (2006.01) A61K 31/662 (2006.01) A61P 9/06 (2006.01) A61P 35/00 (2006.01) A61P 37/06 (2006.01) C07F 9/38 (2006.01)

Patent

CA 2590748

The present invention provides compounds that have antagonist activity at the S1P1 and/or S1P3 receptors. These compounds have enhanced selectivity and potency at the S1P1 and/or S1P3 receptors.

L'invention concerne des composés présentant une activité antagoniste sur les récepteurs S1P1 et/ou S1P3. Ces composés possèdent une sélectivité améliorée et une puissance sur les récepteurs S1P1 et/ou S1P3.

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