C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 487/08 (2006.01) A61K 31/395 (2006.01) A61K 31/439 (2006.01) A61K 31/551 (2006.01) A61P 25/00 (2006.01) A61P 25/28 (2006.01) A61P 25/30 (2006.01) A61P 29/00 (2006.01) C07D 471/08 (2006.01)
Patent
CA 2410945
The present invention relates to novel aryl and heteroaryl diazabicycloalkane derivatives, which are found to be cholinergic ligands at the nicotinic acetylcholine receptors and modulators of the monoamine receptors and transporters. Due to their pharmacological profile the compounds of the invention may be useful for the treatment of diseases or disorders as diverse as those related to the cholinergic system of the central nervous system (CNS), the peripheral nervous system (PNS), diseases or disorders related to smooth muscle contraction, endocrine diseases or disorders, diseases or disorders related to neuro-degeneration, diseases or disorders related to inflammation, pain, and withdrawal symptoms caused by the termination of abuse of chemical substances.
L'invention concerne des dérivés de diazabicycloalkane aryle et hétéroaryle, qui sont des ligands cholinergiques aux récepteurs d'acétylcholine nicotinique et des modulateurs de récepteurs et transporteurs monoamine. Le profil pharmacologique des composés considérés peut être utile pour traiter des maladies ou des troubles aussi divers que ceux qui sont liés au système cholinergique du système nerveux central, ou du système nerveux périphérique, ou bien des maladies ou des troubles liés à la contraction des muscles lisses, des maladies ou des troubles de type endocrinien, ou liés également à la neurodégénérescence, l'inflammation, la douleur et les symptômes de sevrage apparaissant à la désintoxication après un abus de substances chimiques.
Ahring Philip K.
Jorgensen Tino Dyhring
Nielsen Elsebet Ostergaard
Nielsen Simon Feldbaek
Olsen Gunnar M.
Mccarthy Tetrault Llp
Neurosearch A/s
LandOfFree
Aryl and heteroaryl diazabicycloalkanes, their preparation... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Aryl and heteroaryl diazabicycloalkanes, their preparation..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Aryl and heteroaryl diazabicycloalkanes, their preparation... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1718565