C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 235/14 (2006.01) A61K 31/4184 (2006.01) A61K 31/4188 (2006.01) A61P 3/10 (2006.01) C07D 471/04 (2006.01) G01N 33/50 (2006.01)
Patent
CA 2369549
Disclosed are compounds of formula (I) or the pharmaceutically acceptable non- toxic salts thereof wherein X, R1, R2, R3, R4, R5, R6, R7, A, B, C, and D are variables defined herein. Such compounds useful in treatment of obesity and diabetes. The invention also provides labeled probes for the localization of cellular receptors that are involved in the modulation of blood glucose levels.
L'invention concerne des composés de formule (I), ou les sels non toxiques pharmaceutiquement acceptables de ceux-ci, X, R¿1?, R¿2?, R¿3?, R¿4?, R¿5?, R¿6?, R¿7?, A, B, C, et D représentant des variables définies dans la description. Ces composés peuvent être utilisés pour traiter l'obésité et le diabète. L'invention concerne également des sondes marquées permettant de localiser des récepteurs cellulaires qui interviennent dans la modulation des niveaux glycémiques.
Desimone Robert W.
Hutchison Alan
Mbm & Co.
Neurogen Corporation
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