Aryl and heteroaryl fused imidazo[1,5-a]pyrazines as...

Details Aryl and heteroaryl fused imidazo[1,5-a]pyrazines as... Aryl and heteroaryl fused imidazo[1,5-a]pyrazines as...

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) A61K 31/4995 (2006.01) A61P 25/00 (2006.01)

Patent

CA 2706866

The invention relates to imidazo[1,5-a]pyrazine derivatives, to processes for preparing them, to pharmaceutical preparations which comprise these compounds and to the pharmaceutical use of these compounds, which are inhibitors of phospho-diesterase (PDE10), as active compounds for treating central nervous system diseases of mammals, including humans.

L'invention concerne des dérivés d'imidazo[1,5-a]pyrazine, des procédés pour les préparer, des préparations pharmaceutiques qui comprennent ces composés et l'utilisation pharmaceutique de ces composés, qui sont des inhibiteurs de phosphodiestérase 10 (PDE10), en tant que composés actifs pour traiter des maladies du système nerveux central des mammifères, y compris des humains.

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