Aryl and heterocyclyl substituted pyrimidine derivatives as...

Details Aryl and heterocyclyl substituted pyrimidine derivatives as... Aryl and heterocyclyl substituted pyrimidine derivatives as...

A - Human Necessities

61

K

A61K 31/495 (2006.01) C07D 239/24 (2006.01) C07D 401/14 (2006.01) C07D 403/12 (2006.01) C07D 403/14 (2006.01)

Patent

CA 2354040

This invention is directed to aryl and heterocyclyl substituted pyrimidine derivatives selected from formulae (I), (II) and (III), wherein Z1, Z2, R1, R2, R3, R4, R5 and R6 are defined herein. These compounds are useful as anti- coagulants.

L'invention concerne des dérivés de pyrimidine à substitution aryle et hétérocyclyle choisis parmi les formules (I), (II) et (III), dans lesquelles Z?1¿, Z?2¿, R?1¿, R?2¿, R?3¿, R?4¿, R?5¿ et R?6¿ sont définis dans le descriptif. Ces composés sont utiles en tant qu'anticoagulants.

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