Aryl carbamate derivatives, preparation and use thereof

Details Aryl carbamate derivatives, preparation and use thereof Aryl carbamate derivatives, preparation and use thereof

C - Chemistry, Metallurgy

07

D

C07D 295/08 (2006.01) A61K 31/445 (2006.01) A61K 31/495 (2006.01) C07D 213/74 (2006.01) C07D 213/79 (2006.01) C07D 213/84 (2006.01) C07D 237/00 (2006.01) C07D 237/20 (2006.01) C07D 239/42 (2006.01) C07D 241/00 (2006.01) C07D 241/20 (2006.01) C07D 285/10 (2006.01) C07D 295/088 (2006.01) C07D 295/12 (2006.01) C07D 295/14 (2006.01) C07D 333/42 (2006.01) C07D 401/04 (2006.01) C07D 403/04 (2006.01)

Patent

CA 2438828

The invention relates to novel compounds, the preparation and use, particularly therapeutic, thereof. More specifically, the invention relates to compounds derived from aryl carbamates, the preparation and use thereof, particularly in the field of human and animal health. According to the invention, the compounds are preferably 5-HT4 serotoninergic receptor ligands and can therefore be used in the therapeutic or prophylactic treatment of any disorder involving a 5-HT4 receptor. The invention also relates to pharmaceutical compositions comprising such compounds, the preparation and use thereof and treatment methods using said compounds.

La présente invention concerne de nouveaux composés, leur préparation et leurs utilisations, notamment thérapeutiques. Elle concerne plus particulièrement des composés dérivés d'arylcarbamates, leur préparation et leurs utilisations, notamment dans le domaine de la santé humaine ou animale. Les composés selon l'invention sont préférentiellement des ligands des récepteurs sérotoninergiques 5-HT4, et sont donc utilisables dans le traitement thérapeutique ou prophylactique de tout désordre impliquant un récepteur 5- HT4. La présente invention concerne également des compositions pharmaceutiques comprenant de tels composés, leur préparation et leurs utilisations, ainsi que des méthodes de traitement utilisant lesdits composés.

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