Aryl ether substituted imidazoquinolines

Details Aryl ether substituted imidazoquinolines Aryl ether substituted imidazoquinolines

C - Chemistry, Metallurgy

07

D

C07D 471/04 (2006.01) A61K 31/437 (2006.01) A61P 31/12 (2006.01) A61P 35/00 (2006.01) C07D 221/00 (2006.01) C07D 235/00 (2006.01)

Patent

CA 2430844

Imidazoquinoline and tetrahydroimidazoquinoline compounds that contain ether and aryl or alkenyl functionality at the 1-position are useful as immune response modifiers. The compounds and compositions of the invention can induce the biosynthesis of various cytokines and are useful in the treatment of a variety of conditions including viral diseases and neoplastic diseases.

Cette invention concerne des composés d'imidazoquinoline et de tétrahydroimidazoquinoline comprenant une fonctionnalité éther et aryle ou alcényle en position 1 et qui sont utiles en tant que modificateurs des réponses immunitaires. Les composés et compositions selon l'invention peuvent induire la biosynthèse de diverses cytokines et conviennent bien pour le traitement de diverses pathologies, dont des maladies virales et néoplasiques.

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