Aryl fused azapolycyclic compounds

Details Aryl fused azapolycyclic compounds Aryl fused azapolycyclic compounds

C - Chemistry, Metallurgy

07

H

C07H 19/23 (2006.01) A61K 31/498 (2006.01) A61K 31/706 (2006.01) A61P 25/00 (2006.01) C07D 451/00 (2006.01) C07H 13/12 (2006.01) C07H 7/033 (2006.01)

Patent

CA 2468717

This invention is directed to compounds of formula (1) and their pharmaceutically acceptable salts, wherein R1, R2, and R3 are as defined herein; intermediates for the synthesis of such compounds; and methods of using such compounds in the treatment of nicotine addiction/withdrawal and CNS disorders.

Cette invention a trait à des composés correspondant à la formule (I) ainsi qu'à leurs sels acceptables du point de vue pharmaceutique. Dans cette formule, R?1¿, R?2¿ et R?3¿ sont tels que définis dans le descriptif. L'invention concerne également des intermédiaires entrant dans la synthèse de ces composés ainsi que l'usage qui est fait de ces composés pour traiter l'assuétude à la nicotine et des troubles du système nerveux central.

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