Aryl hydantoins

Details Aryl hydantoins Aryl hydantoins

C - Chemistry, Metallurgy

07

D

260/315.05, 260/

C07D 233/76 (2006.01) C07D 233/74 (2006.01) C07D 233/78 (2006.01) C07D 233/96 (2006.01) C07D 403/06 (2006.01)

Patent

CA 1120481

ABSTRACT Hydantoin compounds are described, having the following formula Image (I) wherein Ar is phenyl optioally substituted by up to three radicals selected from the group comprising C1-6 alkoxy, halogen, 1,3-dioxol-2-yl, hydroxy C1-4 alkoxy C1-4 alkyl, phenyl, hydroxyl, nitrile, C1-4 haloalkyl, C1-4 alkyl, C2-4 alkenyloxy, C1-4 alkoxycarbonyl or phenoxy optionally substituted by C1-4 haloalkyl, C1-4 alkoxy or halogen; or is thiophena optionally substituted by phenyl or by one or two C1-4 alkyl groups; R1 and R2 are independently hydrogen or taken together represent a chemical bond; R3 is hydrogen, C1-6 alkyl or C2-4 alkenyl; and R4 is C1-6 alkyl; C2-4 alkenyl, phenyl or benzyl; provided that R3 cannot be hydrogen when Ar is unsubstituted phenyl and R4 is n-butyl. The compounds are useful in the prophylactic treatment of asthma in mammals.

327985

Affiliated with

Also associated with

Rating

Aryl hydantoins does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Aryl hydantoins, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Aryl hydantoins will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1146870