A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/535 (2006.01) A61K 31/495 (2006.01) A61K 31/498 (2006.01) A61K 31/538 (2006.01)
Patent
CA 2220517
Methods are disclosed for treating a mammal with a condition that responds to .alpha.-2 agonist treatment without causing cardiovascular side effects using compounds of formula (II) wherein R1 is H, alkyl of 1 to 4 carbon atoms or a halogen atom, X is O or NH and A is H or an oxo group and wherein said compound does not cause a concomitant reduction in blood pressure of said mammal.
Cette invention concerne des procédés permettant de traiter un mammifère dont l'état justifie un traitement d'agent agoniste alpha-2, et ce sans induire d'effets secondaires cardio-vasculaires. Ces procédés font usage de composé représenté par la formule (II) dans laquelle R1 est H, alkyle ayant de 1 à 4 atomes de carbone ou un atome d'halogène, X est O ou NH et A est H ou un groupe oxo, ce composé ne provoquant aucune réduction concomitante de la pression sanguine chez le mammifère traité.
Burke James A.
Lai Ronald K.
Munk Stephen A.
Allergan
Allergan Inc.
Gowling Lafleur Henderson Llp
LandOfFree
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