C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 207/08 (2006.01) A61K 31/40 (2006.01) A61K 31/439 (2006.01) A61K 31/445 (2006.01) A61K 31/46 (2006.01) A61P 25/24 (2006.01) C07D 211/32 (2006.01) C07D 401/10 (2006.01) C07D 403/06 (2006.01) C07D 405/06 (2006.01) C07D 451/02 (2006.01) C07D 487/04 (2006.01)
Patent
CA 2728373
This invention pertains to aryl pyrrolidinyl and piperidinyl ketone compounds of formula (I) wherein R1 and R2 are as described herein, as well as pharmaceutically acceptable salts and esters thereof, and methods for using the same. In particular, compounds of the present invention are useful for treatment of diseases associated with monoamine reuptake inhibition.
L'invention concerne des composés d'arylpyrrolidinyle et de piperidinyl cétone représentés par la formule (I), dans laquelle R1 et R2 sont tels que définis dans la description ainsi que des sels pharmaceutiquement acceptables et des esters de ceux-ci, et des méthodes utilisant lesdits composés. Les composés de l'invention sont utiles, en particulier pour traiter les maladies associées à l'inhibition de la recapture des monoamines.
Iyer Pravin
Lin Clara Jeou Jen
Lucas Matthew C.
Lynch Stephen M.
Madera Ann Marie
Borden Ladner Gervais Llp
F.hoffmann-La Roche Ag
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