(aryl or heteroaromatic methyl)-2,2'-bi-1h-imidazoles

Details (aryl or heteroaromatic methyl)-2,2'-bi-1h-imidazoles (aryl or heteroaromatic methyl)-2,2'-bi-1h-imidazoles

C - Chemistry, Metallurgy

07

D

167/233, 260/302

C07D 403/04 (2006.01) C07D 233/54 (2006.01) C07D 405/14 (2006.01) C07D 409/14 (2006.01) C07D 417/14 (2006.01)

Patent

CA 1338786

This invention relates to novel (aryl or heteroaromatic methyl)-2,2'-1H-biimidazoles; to a process for their production comprising of reacting an appropriate alpha-brominated or alpha-chlorinated, substituted or non- substituted, methylated monoaromatic ring compound with 2,2'-bi-1H-imidazole in a solvent such as ethanol in the presence of a base such as sodium hydroxide under reflux conditions; and to pharmaceutical compositions and methods of treating hypertension with such compounds.

572886

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