Aryl substituted 8-azabicyclo[3.2.1]octane compounds as...

Details Aryl substituted 8-azabicyclo[3.2.1]octane compounds as... Aryl substituted 8-azabicyclo[3.2.1]octane compounds as...

C - Chemistry, Metallurgy

07

D

C07D 451/06 (2006.01) A61K 31/46 (2006.01) A61P 3/04 (2006.01) C07D 451/02 (2006.01) C07D 451/04 (2006.01)

Patent

CA 2581745

Aryl substituted 8-azabicyclo[3.2.1]octane compounds and analogues thereof, are provided. Such compounds may be used to modulate MCH binding to MCH receptors in vivo or in vitro, and are particularly useful in the treatment of a variety of metabolic, feeding, neuropsychiatric, reproductive and sexual disorders in humans, domesticated companion animals and livestock animals. Pharmaceutical compositions and methods for treating such disorders are provided, as are methods for using such ligands for detecting MCH receptors (e.g., receptor localization studies).

L'invention concerne des composés de 8-azabicyclo[3.2.1]octane à substitution aryle et des analogues de ceux-ci. Ces composés peuvent servir à moduler la liaison de MCH aux récepteurs de MCH in vivo ou in vitro, et sont particulièrement utiles dans le traitement de divers troubles métaboliques, de l'alimentation, neuropsychiatriques, sexuels et de la reproduction chez l'être humain, les animaux de compagnie domestiqués et le bétail. L'invention concerne des compositions pharmaceutiques et des méthodes de traitement de tels troubles, ainsi que des procédés d'utilisation de ces ligands pour détecter des récepteurs de MCH (e.g., études de localisation de récepteurs).

Affiliated with

Also associated with

Rating

Aryl substituted 8-azabicyclo[3.2.1]octane compounds as... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Aryl substituted 8-azabicyclo[3.2.1]octane compounds as..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Aryl substituted 8-azabicyclo[3.2.1]octane compounds as... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1727525