C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 235/18 (2006.01) A61K 31/4184 (2006.01) A61P 35/00 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01)
Patent
CA 2572218
Aryl substituted benzimidazole and imidazo[4,5]Aryl substituted benzimidazole and imidazo[4,5]Aryl substituted benzimidazole and imidazo[4,5]pyridine ethers are described as inhibitors of Cds1 and useful as adjuvants to chemotherapy or radiation therapy in the treatment of cancer.
L'invention concerne des éthers benzimidazole à substitution aryle et benzimidazole à substitution aryle imidazo[4,5] et benzimidazole à substitution aryle imidazo[4,5] et imidazo[4,5] pyridine qui sont des inhibiteurs de Cds1, utiles comme adjuvants pour la chimiothérapie ou la radiothérapie dans le traitement du cancer.
Breitenbucher J. Guy
Lee-Dutra Alice
Neff Danielle K.
Janssen Pharmaceutica N.v.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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