C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 285/14 (2006.01) C07D 417/04 (2006.01) C07D 417/06 (2006.01)
Patent
CA 2671844
The present invention is directed to aryl sulfamide derivatives of formula (I): or a pharmaceutically acceptable salt, stereoisomer or tautomer thereof, which are monoamine reuptake inhibitors, compositions containing these derivatives, and methods of their use for the prevention and treatment of conditions, including, inter alia, vasomotor symptoms, sexual dysfunction, gastrointestinal disorders and genitourinary disorder, depression disorders, endogenous behavioral disorders, cognitive disorders, diabetic neuropathy, pain, and other diseases or disorders.
La présente invention concerne des dérivés d'aryl sulfamide de formule (I) ou un sel pharmacocompatible, un stéréoisomère ou un tautomère de ceux-ci, qui sont des inhibiteurs du recaptage de la monoamine, des compositions contenant ces dérivés, et leurs méthodes d'utilisation dans la prévention et le traitement de troubles comprenant, entres autres, des symptômes vasomoteurs, des dysfonctions sexuelles, des troubles gastrointestinaux et des troubles génito-urinaires, des troubles associés à la dépression, des troubles endogènes du comportement, des troubles cognitifs, la neuropathie diabétique, des douleurs et autres maladies ou troubles.
Cohn Stephen Todd
Crawley Matthew L.
Fensome Andrew
Goldberg Joel Adam
Jenkins Douglas John
Smart & Biggar
Wyeth
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