Aryl sulfonyls as factor xa inhibitors

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 417/12 (2006.01) A61K 31/275 (2006.01) A61K 31/33 (2006.01) A61K 31/4155 (2006.01) A61K 31/423 (2006.01) A61K 31/428 (2006.01) A61P 7/02 (2006.01) C07D 409/12 (2006.01) C07D 409/14 (2006.01) C07D 413/14 (2006.01) C07D 417/14 (2006.01)

Patent

CA 2368630

The present application describes aryl sulfonyls of formula (I) or pharmaceutically acceptable salt or prodrug forms thereof, wherein D, E, and M are defined below, are effective factor Xa inhibitors.

La présente invention concerne des sulfonyles aryles de formule I, ou des formes salines ou des promédicaments pharmaceutiquement acceptables de ceux-ci. Dans cette formule, D, E, et M sont tels que définis dans la description, les sulfonyles aryles de cette invention étant de puissants inhibiteurs du facteur Xa.

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