Aryl thiopyrano(2,3,4-c,d)indoles as inhibitors of...

Details Aryl thiopyrano(2,3,4-c,d)indoles as inhibitors of... Aryl thiopyrano(2,3,4-c,d)indoles as inhibitors of...

C - Chemistry, Metallurgy

07

D

C07D 495/06 (2006.01) A61K 31/395 (2006.01) C07D 519/00 (2006.01)

Patent

CA 2149429

2149429 9411378 PCTABS00032 Compounds having formula (I) are inhibitors of 5-lipoxygenase and inhibitors of leukotriene biosynthesis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating angina, cerebral spasm, glomerular nephritis, hepatitis, endotoxemia, psoriasis, uveitis, and allograft rejection and in preventing the formation of atherosclerotic plaques.

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