Aryl-triflates and related compounds

Details Aryl-triflates and related compounds Aryl-triflates and related compounds

A - Human Necessities

61

K

A61K 31/55 (2006.01) A61K 31/255 (2006.01) A61K 31/35 (2006.01) A61K 31/40 (2006.01) A61K 31/445 (2006.01) A61K 31/54 (2006.01) C07C 309/65 (2006.01) C07D 209/16 (2006.01) C07D 213/50 (2006.01) C07D 221/18 (2006.01) C07D 221/28 (2006.01) C07D 223/16 (2006.01) C07D 307/81 (2006.01) C07D 333/20 (2006.01) C07D 455/02 (2006.01) C07D 471/04 (2006.01)

Patent

CA 2126242

2126242 9311761 PCTABS00022 Aryltriflates and related compounds having general formula (1) wherein Ar is an aromatic or heteroaromatic system of a compound which has a therapeutic, biological activity when it, in the same position, carries a hydroxy, alkyloxy, halo, ester or cyano group; wherein R1 is CF3, (C1-C8)alkyl, -CH2-(C3-C8)cycloalkylalkyl, substituted phenyl, substituted benzyl, substituted phenylethyl, substituted phenylpropyl, substituted 2-thiophenylethyl or substituted 2-thiophenylpropyl; possess both good pharmacodynamic and good pharmacokinetic properties and are thus useful drugs.

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