C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 401/04 (2006.01) A61K 31/4523 (2006.01) A61K 31/454 (2006.01) A61K 31/4545 (2006.01) A61P 9/14 (2006.01) A61P 11/06 (2006.01) A61P 37/08 (2006.01) C07D 205/085 (2006.01) C07D 211/58 (2006.01) C07D 221/00 (2006.01) C07D 239/00 (2006.01) C07D 333/00 (2006.01) C07D 401/14 (2006.01) C07D 409/14 (2006.01) C07D 417/04 (2006.01) C07D 471/04 (2006.01) C07D 495/04 (2006.01)
Patent
CA 2387613
The invention relates to compounds of general formula R-Z1-Z2-Z3-R1 wherein R. R1 and Z1 -Z3 are defined as in Claim 1, the tautomers thereof, diastereomers thereof, enantiomers thereof, mixtures and salts thereof, especially the physiologically compatible salts thereof with inorganic or organic acids and bases, exhibiting valuable pharmacological properties, especially CGRP antagonistic properties. The invention also relates to medicaments containing the above-mentioned compounds, the use thereof and method for the production thereof.
L'invention concerne des composés de formule générale Z?1¿-Z?2¿-Z?3¿-R?1¿, dans laquelle R, R?1¿ et Z?1¿ à Z?3¿ sont tels que définis dans la revendication 1, ainsi que leurs tautomères, leurs diastéréomères, leurs énantiomères, leurs mélanges et leurs sels, en particulier leurs sels physiologiquement compatibles avec des acides inorganiques ou organiques ou des bases, présentant des propriétés pharmacologiques précieuses, en particulier des propriétés antagonistes CGRP. L'invention concerne en outre des médicaments contenant les composés précités, leur utilisation et leur procédé de fabrication.
Bauer Eckhart
Doods Henri
Eberlein Wolfgang
Engel Wolfhard
Hallermayer Gerhard
Boehringer Ingelheim Pharma Gmbh & Co. Kg
Boehringer Ingelheim Pharma Kg
Fetherstonhaugh & Co.
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