C - Chemistry – Metallurgy – 12 – P
Patent
C - Chemistry, Metallurgy
12
P
C12P 41/00 (2006.01) C12P 7/40 (2006.01)
Patent
CA 2116004
2116004 9304190 PCTABS00020 In a process for preparing predominantly one enantiomer of an optically-active 2-arylalkanoic acid by biotransformation, using an appropriate enzyme, of a mixture of enantiomers of an ester of the acid, the ester is derived from an alcohol of more than 4 carbon atoms, and the enzyme is in crude or only partially purified form. For example, S-ketoprofen can be thus prepared economically and in high ee, from racemic octyl ketoprofen.
Carganico Germano
Evans Christopher T.
Mccague Raymond
Taylor Stephen J. C.
Kirby Eades Gale Baker
Laboratorios Menarini S.a.
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