Arylalkoxycoumarins, their preparation and therapeutic...

Details Arylalkoxycoumarins, their preparation and therapeutic... Arylalkoxycoumarins, their preparation and therapeutic...

C - Chemistry, Metallurgy

07

D

167/244, 260/358

C07D 311/08 (2006.01) A61K 31/37 (2006.01) C07D 311/16 (2006.01) C07D 311/80 (2006.01)

Patent

CA 1336001

Arylalkoxycoumarins of the general formula I Image I where R1 and R2 independently of one another are each hydrogen, lower alkyl, phenyl or halogen, or the two radicals together form an alkylene bridge of 3 to 5 carbon atoms, R3 is lower alkyl or halogen, n is an integer of from 0 to 3, m is an integer of from 0 to 4, R4 is hydrogen or lower alkyl and Ar is a phenyl ring which is monosubstituted to trisubstituted by halogen, C1-C6-alkyl or C1-C6-alkoxy or monosubstituted by nitro, cyano or trifluoromethyl or is a naphthyl ring, with the proviso that m is not 0 when Ar is unsubstituted phenyl, processes for their preparation, and drugs prepared therefrom. These compounds are particularly useful for the treatment of disorders of the central nervous system.

614973

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