C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
167/179, 260/295
C07C 211/27 (2006.01) A61K 31/135 (2006.01) A61K 31/137 (2006.01) A61K 31/165 (2006.01) A61K 31/275 (2006.01) A61K 31/44 (2006.01) C07C 211/29 (2006.01) C07C 215/52 (2006.01) C07C 217/60 (2006.01) C07C 237/06 (2006.01) C07C 237/08 (2006.01) C07C 237/10 (2006.01) C07C 255/58 (2006.01) C07C 271/12 (2006.01)
Patent
CA 1341136
The invention provides the use; of a compound of formula I, (see formula I) wherein Ar1 and Ar2 independently represent phenyl substituted by one or more of amino, nitro, chlorine, bromine, hydroxy, C1-6 alkoxy, C1-6 alkyl or cyano; in addition one of Ar1 or Ar2 may represent phenyl; R1 represents hydrogen or C1-6 alkyl; R2 represents hydrogen or COCH2NH2; R3 represents hydrogen or C1-6 alkyl; in addition, when R2 represents hydrogen, then both of Ar1 and Ar2 may represent phenyl, one or both of Ar, and Ar2 may represent fluorophenyl or 2-, 3- or 4- pyridinyl, and R1 may represent C1-6 alkoxycarbonyl or trifluoromethyl; with certain provisos; or a pharmaceutically acceptable salt thereof; as a neuroprotective or anticonvulsive agent, which comprises administration of the compound of formula I, or a pharmaceutically acceptable salt thereof, to a patient in need of such treatment.
608107
Griffith Ronald C.
Napier James J.
Astra Ab
Griffith Ronald C.
Napier James J.
Ridout & Maybee Llp
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