¬(arylalkylpiperidin-4-yl)methyl|-2a,3,4,5-tetrahydro-1(2h)...

Details ¬(arylalkylpiperidin-4-yl)methyl|-2a,3,4,5-tetrahydro-1(2h)... ¬(arylalkylpiperidin-4-yl)methyl|-2a,3,4,5-tetrahydro-1(2h)...

C - Chemistry, Metallurgy

07

D

C07D 211/18 (2006.01) A61K 31/445 (2006.01) C07D 211/22 (2006.01) C07D 211/30 (2006.01) C07D 405/10 (2006.01)

Patent

CA 2070714

HOE 91/S 013 ABSTRACT There are disclosed various compounds of the formula below Image (I) where X is hydrogen, loweralkyl, loweralkoxy, hydroxy or nitro; Y is hydrogen or loweralkoxy; or alternatively, X ans Y combined together form the group -OCH2O- in which case the positions of X and Y on the benzene ring moiety must be adjacent to each other; Z is hydrogen, loweralkyl, loweralkoxy, hydroxy, halogen or nitro and n is 0 or 1, which compounds are useful for alleviating various memory dysfunction characterizied by a cholinergic deficit such as Alzheimer's disease.

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