Arylamine ketones, their preparation methods, the...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 211/14 (2006.01) A61K 31/445 (2006.01) A61K 31/4965 (2006.01) A61K 31/535 (2006.01) A61P 7/02 (2006.01) A61P 29/00 (2006.01) C07D 211/18 (2006.01) C07D 211/20 (2006.01) C07D 211/22 (2006.01) C07D 211/36 (2006.01) C07D 211/60 (2006.01) C07D 211/62 (2006.01) C07D 211/64 (2006.01) C07D 211/66 (2006.01) C07D 241/04 (2006.01) C07D 265/30 (2006.01) C07D 265/32 (2006.01) C07D 295/108 (2006.01) C07D 295/15 (2006.01)

Patent

CA 2576830

Disclosed Arylamine ketones of formula (I), their preparation methods, the pharmaceutical compositions containing them and their use in preventing and/or treating the diseases related to the plaque-activating factors, especially in anti-inflammation and immunization, more especially in the treatment of the acute or chronic inflammation, such as, osteoarthritis, oarthritis deformans, etc..

La présente invention concerne des cétones d'arylamine représentées par la formule (I), des procédés de préparation de ces dernières, des compositions pharmaceutiques renfermant ces cétones d'arylamine et l'utilisation de ces dernières dans la prévention et/ou le traitement des maladies associées aux facteurs d'activation de la plaque, notamment pour lutter contre l'inflammation et pour provoquer l'immunisation, plus spécifiquement dans le traitement de l'inflammation aiguë ou chronique, telle que l'arthrose, la polyarthrite rhumatoïde et autres.

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