Arylamine-substituted quinazolinone compounds

C - Chemistry – Metallurgy – 07 – D

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C07D 417/12 (2006.01) A61K 31/517 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01) C07D 413/12 (2006.01)

Patent

CA 2530312

Compounds represented by Formula (I) which are useful as are alpha-1A/B adrenoceptor antagonists, to methods of treating conditions associated with the activity of alpha-1A/B adrenoceptors, and to methods of making said compounds, wherein Ar, Z, R, R', R5 and R10 are as defined herein.

L'invention concerne des composés représentés par la formule (I) utilisés comme antagonistes de l'alpha-1A/B adrénocepteur, des méthodes permettant de traiter des états associés à l'activité des alpha-1A/B adrénocepteurs, et des procédés permettant de produire lesdits composés, Ar, Z, R, R', R?5¿ et R?10¿ étant définis dans la description.

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