Arylamines for the treatment of conditions associated with...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 213/73 (2006.01) A61K 31/4025 (2006.01) A61K 31/41 (2006.01) A61K 31/4427 (2006.01) A61K 31/444 (2006.01) A61K 31/455 (2006.01) A61K 31/496 (2006.01) A61K 31/497 (2006.01) A61P 17/14 (2006.01) A61P 25/18 (2006.01) A61P 25/28 (2006.01) C07C 233/78 (2006.01) C07C 311/17 (2006.01) C07C 311/29 (2006.01) C07C 311/53 (2006.01) C07D 207/09 (2006.01) C07D 207/12 (2006.01) C07D 207/14 (2006.01) C07D 207/48 (2006.01) C07D 211/96 (2006.01) C07D 213/42 (2006.01) C07D 213/75 (2006.01) C07D 213/82 (2006.01) C07D 233

Patent

CA 2452686

The present invention relates to new compounds of formula (I) wherein Z, Y, X, P, Q, R, R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, A, m and n are defined as in any one of claims 1 to 3, a process for their preparation and new intermediates prepared therein, pharmaceutical formulations containing said therapeutically active compounds and to the use of said active compounds for the treatment of conditions associated with glycogens synthase kinase-3 (GSK3).

L'invention concerne de nouveaux composés de formule (I), dans laquelle Z, Y, X, P, Q, R, R?1¿, R?2¿, R?3¿, R?4¿, R?5¿, R?6¿, R?7¿, R?8¿, R?9¿, R?10¿, R?11¿, R?12¿, A, m et n sont définis comme dans une quelconque des revendications 1 à 3, un procédé pour leur préparation et de nouveaux intermédiaires préparés par ce procédé, des formulations pharmaceutiques contenant lesdits composés thérapeutiquement actifs et l'utilisation des ces composés actifs dans une thérapie.

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