C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 307/68 (2006.01) A61K 31/34 (2006.01) A61K 31/38 (2006.01) A61P 9/06 (2006.01) C07D 333/38 (2006.01)
Patent
CA 2431095
The invention relates to arylated furane and thiophene carboxylic acid amides, a method for the production thereof, the use thereof as medicaments, in addition to pharmaceutical preparations containing the compounds of formula (Ia) and (Ib) wherein X, R(1), R(2), R(3), R(4), R(5), R(6), R(7), R(30) and R(31) have the same meaning as cited in the claims. According to the invention, the compounds are particularly suitable as novel anti-arrhythmic active ingredients, particularly for the treatment and prophylaxis of atrial arrhythmia for example, atrial fibrillation, AF, or atrial flutter.
L'invention concerne les composés des formules (Ia) et (Ib) dans lesquelles X, R(1), R(2), R(3), R(4), R(5), R(6), R(7), R(30) et R(31) possèdent la signification donnée dans le descriptif. Les composés selon l'invention servent particulièrement de nouveaux agents actifs antiarythmiques, notamment pour le traitement et la prophylaxie d'arythmies auriculaires, par ex. de fibrillation auriculaire ou de flutter auriculaire.
Brendel Joachim
Hemmerle Horst
Kleemann Heinz-Werner
Peukert Stefan
Aventis Pharma Deutschland Gmbh
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Sanofi-Aventis Deutschland Gmbh
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