C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/168, 260/175
C07D 239/42 (2006.01) C07C 245/08 (2006.01) C07D 213/76 (2006.01) C07D 239/69 (2006.01) C07D 263/50 (2006.01)
Patent
CA 1171409
ABSTRACT OF THE DISCLOSURE Novel arylazo compounds and processer for their prep- aration are provided herein. Such arylazo compounds are of the general Formula I Image (I) wherein R1 and R2 independently of each other represent hydro- gen or C1-3 alkyl, R3 represents hydrogen, halogen, C1-3 alkyl, C1-3 alkoxy, carboxy, C1-3 alkoxycarbonyl, C1-3 alkylcarbonyl or a group X-NH-SO2-, wherein X represents a heterocyclic ring, R4 represents hydrogen, halogen or C1-3 alkyl, and n is the integer 1 or 2, the two groups Image being the same or dif- ferent when n is 2, and lactones and salts thereof. These compounds may be prepared using a diazotizing reaction followed by a coupling reaction, or by the reaction of a sulfonyl chloride. The compounds of Formula 1 have a high inhibiting effect on prostaglandin synthetizing fertility agent.
353699
Agback Karl H.
Borden Ladner Gervais Llp
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