C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 239/70 (2006.01) A61K 31/505 (2006.01) A61K 31/5355 (2006.01) C07D 221/16 (2006.01) C07D 401/04 (2006.01) C07D 401/06 (2006.01) C07D 401/12 (2006.01) C07D 405/04 (2006.01) C07D 405/12 (2006.01) C07D 409/04 (2006.01) C07D 417/04 (2006.01)
Patent
CA 2540686
This invention provides novel arylindenopyridines and arylindenopyrimidines of formula (I), (II) wherein R1, R2, R3, R4, and X are as defined above, and pharmaceutical compositions comprising same, useful for treating disorders ameliorated by antagonizing adenosine A2a receptors. This invention also provides therapeutic and prophylactic methods using the instant compounds and pharmaceutical compositions.
Cette invention concerne de nouvelles arylindénopyridines et arylindénopyrimidines représentées par la formule (I), (II), où R¿1?, R¿2?, R¿3?, R¿4? et X sont tels que définis dans les pièces descriptives de la demande, ainsi que des compositions pharmaceutiques comprenant ces composés, qui sont utiles pour traiter les affections susceptibles d'être améliorées par antagonisme des récepteurs d'adénosine A2a. Cette invention concerne également des procédés thérapeutiques et prophylactiques utilisant ces composés et ces compositions pharmaceutiques.?¿
Bullington James L.
Heintzelman Geoffrey R.
Rupert Kenneth C.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
Ortho-Mcneil Pharmaceutical Inc.
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