Arylindenopyridines with pde inhibiting activity

Details Arylindenopyridines with pde inhibiting activity Arylindenopyridines with pde inhibiting activity

C - Chemistry, Metallurgy

07

D

C07D 405/04 (2006.01) A61K 31/473 (2006.01) A61P 7/00 (2006.01) A61P 11/06 (2006.01) A61P 29/00 (2006.01) A61P 31/18 (2006.01) A61P 37/00 (2006.01) C07D 221/16 (2006.01) C07D 401/04 (2006.01) C07D 409/04 (2006.01)

Patent

CA 2445188

This invention provides novel arylindenopyridines of the formula (I), and pharmaceutical compositions comprising same, useful for treating disorders ameliorated by reducing PDE activity in appropriate cells. This invention also provides therapeutic and prophylactic methods using the instant pharmaceutical compositions.

La présente invention concerne des nouvelles arylindénopyridines représentées par la formule (I) et des compositions pharmaceutiques comprenant ces dernières, qui sont utiles pour traiter des troubles qui sont améliorés lorsque l'activité PDE est réduite dans les cellules appropriées. Cette invention concerne également des méthodes thérapeutiques et prophylactiques dans lesquelles on utilise les compositions pharmaceutiques selon la présente invention. Formule (I)

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