Aryloxazole, aryloxadiazole and benzimidazole derivatives

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 413/12 (2006.01) A61K 31/454 (2006.01) A61P 3/10 (2006.01) C07D 401/12 (2006.01)

Patent

CA 2688594

This invention relates to compounds of the formula (I) wherein X is O or NR8, Y is CR7 or N, and R1 to R8 are as defined in the specification, and pharmaceutically acceptable salts thereof. The invention further relates to pharmaceutical compositions containing such compounds, to a process for their preparation and to their use for the treatment and/or prevention of diseases which are associated with the modulation of SST receptors subtype 5.

La présente invention concerne des composés de formule (I) dans laquelle : X est O ou NR8, Y est CR7 ou N, et R1 à R8 sont tels que définis dans la description, ainsi que leurs sels pharmaceutiquement acceptables. L'invention concerne également des compositions pharmaceutiques contenant de tels composés, leur procédé de préparation et leur utilisation pour le traitement et/ou la prévention de maladies liées à la modulation de récepteurs sous-type 5SST.

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